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[Hemodialysis and metabolic disorders].

H Klinkmann, M Holtz, E Kröger

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |June 1, 1978
    PubMed
    Summary

    This study details specific pathophysiological disturbances in dialysis patients, linking metabolic changes from therapy to unique uraemic conditions. Understanding these metabolic shifts is crucial for managing chronic kidney disease patients on dialysis.

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    Adaptation of uraemic patients to anaemia: A31 P nuclear magnetic resonance study.

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2013

    Area of Science:

    • Nephrology
    • Metabolic Medicine
    • Physiology

    Context:

    • Chronic dialysis programs significantly alter patient physiology.
    • Uraemia presents complex metabolic challenges.
    • Aldosterone plays a role in fluid and electrolyte balance.

    Purpose:

    • To develop a concept of specific dialysis-conditioned pathophysiological disturbances.
    • To investigate water, electrolyte, protein, lipid, and hormone metabolism in dialysis patients.
    • To understand the influence of apparative (dialysis) therapy on uraemic pathophysiology.

    Summary:

    • Investigations into water, electrolyte, protein, lipid, and hormone metabolism (including aldosterone) in chronic dialysis patients.
    • Identified specific pathophysiological disturbances linked to dialysis therapy.

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  • Metabolic changes induced by dialysis significantly impact uraemic mechanisms.

    • Impact:

    • Provides a framework for understanding dialysis-specific pathophysiology.
    • Highlights the critical role of metabolic alterations in uraemic patients.
    • Informs clinical management strategies for patients undergoing chronic dialysis.