Molecular aspects of polyvalent sensitization of erythrocytes by proteins

The role of the size of the protein molecule in polyvalent sensitization of erythrocytes was studied. The significance of the molecular parameters of protein sensitins was demonstrated by their blocking each other's accessible antigenic determinants. Steric disturbances increased with the increase in the surface density of the proteins and with differences in their molecular mass. The significance of the molecular parameters of the proteins for the surface architectonics of artificial and natural surfaces is discussed.