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Revascularization for preservation of renal function in patients with atherosclerotic renovascular disease
Insights
Revascularization for atherosclerotic renovascular disease can preserve or improve kidney function. This study shows 67% of patients experienced improved renal function after the procedure.
Area of Science:
- Nephrology
- Cardiovascular Surgery
- Vascular Medicine
Background:
- Atherosclerotic renovascular disease affects renal function and blood pressure.
- Revascularization is a potential treatment to preserve kidney function.
Purpose of the Study:
- To evaluate the effectiveness of elective revascularization in preserving renal function in patients with atherosclerotic renovascular disease.
- To assess the impact of revascularization on renal function in patients with preoperative serum creatinine levels >= 2.0 mg/dL and < 2.0 mg/dL.
Main Methods:
- Fifty-one patients with atherosclerotic renovascular disease underwent elective revascularization.
- Preoperative blood pressure was controlled with medical therapy.
- Postoperative follow-up ranged from 4 to 76 months.
Main Results:
- Vascular reconstruction was technically successful in all patients.
- Renal function improved in 67% of patients (34/51).
- Renal function remained unchanged in 27% (14/51) and deteriorated in 6% (3/51).
Conclusions:
- Elective revascularization is effective in preserving or improving renal function in selected patients with atherosclerotic renal artery disease.
- The procedure demonstrates a high success rate and positive impact on renal function.
- Revascularization should be considered for patients with atherosclerotic renovascular disease aiming for renal function preservation.
Abstract:
Fifty-one patients with atherosclerotic renovascular disease have undergone elective revascularization primarily to preserve renal function. In all patients the blood pressure was well controlled preoperatively with medical therapy and was not an indication for revascularization. The preoperative serum creatinine value was 2.0 mg./dl. or more in 35 patients and less than 2.0 mg./dl. in 16. Vascular reconstruction was technically successful in all patients, with postoperative followup ranging from 4 to 76 months. The current level of over-all renal function is improved in 34 patients (67 per cent), unchanged in 14 (27 per cent) and deteriorated in 3 (6 per cent). In selected patients with atherosclerotic renal artery disease revascularization can achieve preservation or improvement of renal function.