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Recurrent pulmonary embolism.

S Okubo, M Naito, Y Fukunaga

    Japanese Circulation Journal
    |May 1, 1983
    PubMed
    Summary

    Recurrent pulmonary embolism (RPE) can cause severe chronic cor pulmonale. Early diagnosis and treatment are crucial to prevent disease progression, even without leg vein thrombosis.

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    Area of Science:

    • Cardiology
    • Pulmonology
    • Radiology

    Background:

    • Recurrent pulmonary embolism (RPE) is a serious condition often linked to chronic cor pulmonale and pulmonary hypertension.
    • This study examines five RPE cases with severe chronic cor pulmonale, noting the absence of leg thrombophlebitis history.

    Observation:

    • Common symptoms included dyspnea and signs of pulmonary hypertension.
    • Radiological findings revealed focal oligemia, cardiomegaly, plump pulmonary arteries, and multiple perfusion defects on lung scans.
    • Electrocardiograms showed right axis deviation and ischemic changes, while echocardiograms indicated right heart strain and pulmonary artery dilation.

    Findings:

    • Severe gas exchange abnormalities were characteristic of RPE in these cases.
    • Pulmonary hypertension with low cardiac output was a consistent feature.
    • Pulmonary angiograms demonstrated definitive blockages, despite intact leg veins.

    Implications:

    • Emphasizes the critical need for early diagnosis and prompt treatment of acute pulmonary embolism to avert debilitating outcomes.
    • Highlights that RPE can occur without detectable deep vein thrombosis, necessitating a broader diagnostic approach.
    • Suggests that recognizing characteristic imaging and clinical findings is key to managing RPE and preventing progression to severe chronic cor pulmonale.

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