Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A method for equating thermal stress parameters for neurobehavioral toxicity studies.

B J Klauenberg, S B Sparber

    Neurobehavioral Toxicology and Teratology
    |January 1, 1983
    PubMed
    Summary

    Cold and heat stress in rats significantly altered behavior and thermoregulation. This study offers a novel method for quantifying stress intensity using water immersion, valuable for future research on stressor interactions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Food deprivation enhances both autoshaping and autoshaping impairment by a latent inhibition procedure.

    Behavioural processes·2014
    Same author

    Delaying reinforcement in an autoshaping task generates adjunctive and superstitious behaviors.

    Behavioural processes·2014
    Same author

    Electromagnetic field standards in Central and Eastern European countries: current state and stipulations for international harmonization.

    Health physics·2002
    Same author

    Embryonic "binge" cocaine exposure alters neural-immune and neural-endocrine interactions in young chickens: involvement of serotonin(2) receptors.

    Brain research. Developmental brain research·2001
    Same author

    Cocaine and salicylate: documentation of hydroxyl radical formation in hearts and brains of 18-day-old chick embryos and unexpected interactive toxicity.

    Psychopharmacology·2001
    Same author

    Embryonic cocaine exposure and corticosterone: serotonin(2) receptor mediation.

    Pharmacology, biochemistry, and behavior·2001

    Area of Science:

    • Behavioral Neuroscience
    • Stress Physiology
    • Animal Models

    Background:

    • Understanding stress responses is crucial in various scientific fields.
    • Quantifying stressor intensity is essential for experimental control and reproducibility.
    • Existing methods for indexing stress may have limitations.

    Purpose of the Study:

    • To investigate the behavioral effects of acute cold and heat stress in rats.
    • To establish a water immersion procedure as a quantifiable stressor.
    • To explore the relationship between water temperature, exposure duration, and behavioral suppression.

    Main Methods:

    • Rats were exposed to varying temperatures (15-46°C) and durations (1-5 min) of water immersion.
    • Operant behavior on a fixed ratio 15 schedule was assessed 15 minutes post-exposure.

    Related Experiment Videos

  • Colonic temperature was monitored to assess thermoregulatory disruption.

    • Main Results:

    • Exposure to 20°C water for 4 minutes suppressed fixed ratio 15 responding by 53%.
    • Heating water to 44°C, 45°C, and 46°C resulted in 21%, 46%, and 94% suppression, respectively.
    • Significant changes in colonic temperature indicated disrupted thermoregulation and stress induction.

    Conclusions:

    • Water immersion provides a controllable and quantifiable method for inducing stress in rats.
    • This procedure can be used to match qualitatively different stressors behaviorally.
    • The method is useful for studying interactions between stress and other experimental manipulations, such as drug effects.