Carcinoma of the bladder in a patient treated with cyclophosphamide for rheumatoid arthritis

A woman treated with cyclophosphamide for rheumatoid arthritis developed carcinoma of the urinary bladder at the age of 51 years. Several similar cases reported in the literature suggests an increased risk of bladder cancer in patients treated with cyclophosphamide. There is need for a continuous follow-up with urinalysis in patients previously treated with this drug.