Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulsing electromagnetic fields induce cellular transcription.

R Goodman, C A Bassett, A S Henderson

    Science (New York, N.Y.)
    |June 17, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Defining Risk in Alcohol-Associated Liver Disease Using the Model for End-Stage Liver Disease.

    The American journal of gastroenterology·2025
    Same author

    The relationship between exclusion from school and mental health: a secondary analysis of the British Child and Adolescent Mental Health Surveys 2004 and 2007.

    Psychological medicine·2017
    Same author

    The predictors of persistent DSM-IV disorders in 3-year follow-ups of the British Child and Adolescent Mental Health Surveys 1999 and 2004.

    Psychological medicine·2016
    Same author

    Disentangling the autism-anxiety overlap: fMRI of reward processing in a community-based longitudinal study.

    Translational psychiatry·2016
    Same author

    Resilience and corpus callosum microstructure in adolescence.

    Psychological medicine·2015
    Same author

    White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms.

    Molecular psychiatry·2013
    Same journal

    Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

    Science (New York, N.Y.)·2026
    Same journal

    Local signals, systemic decline.

    Science (New York, N.Y.)·2026
    Same journal

    The mechanics of liver regeneration.

    Science (New York, N.Y.)·2026
    Same journal

    Computing in a memory with physics.

    Science (New York, N.Y.)·2026
    Same journal

    Retraction.

    Science (New York, N.Y.)·2026
    Same journal

    Making time.

    Science (New York, N.Y.)·2026
    See all related articles

    Pulsing electromagnetic fields affect gene transcription differently based on pulse type. The single pulse rapidly boosted messenger RNA, while the pulse train showed a delayed effect in dipteran cells.

    Area of Science:

    • Molecular Biology
    • Bioelectromagnetics
    • Cellular Biology

    Background:

    • Weak, pulsing electromagnetic fields (EMFs) are known to influence biological processes.
    • Understanding how EMFs affect cellular functions, like gene transcription, is crucial for potential therapeutic applications.
    • The specific characteristics of EMF pulses may dictate the biological response.

    Purpose of the Study:

    • To investigate if cellular responses to induced currents from electromagnetic fields depend on pulse characteristics.
    • To evaluate the effect of two distinct EMF pulse types on gene transcription in dipteran salivary gland cells.

    Main Methods:

    • Utilized transcription as the target biological process for evaluating EMF effects.
    • Exposed dipteran salivary gland cells to two clinical EMF pulse types: repetitive single pulse and repetitive pulse train.

    Related Experiment Videos

  • Monitored transcription levels using tritiated uridine in transcription autoradiography, cytological nick translation, and isolated RNA fraction analysis.

    • Main Results:

    • The repetitive single pulse significantly increased messenger RNA (mRNA) specific activity at both 15 and 45 minutes post-exposure.
    • The repetitive pulse train also increased mRNA specific activity, but only after a 45-minute exposure period.
    • Distinct differences in transcriptional response were observed between the two pulse types and compared to control groups.

    Conclusions:

    • The characteristics of pulsing electromagnetic fields significantly influence gene transcription.
    • Different EMF pulse types elicit distinct temporal responses in mRNA production.
    • Findings highlight the importance of pulse parameters in bioelectromagnetic interactions and cellular responses.