[Neurohumoral correlations in lumbar pain syndromes]

The hemostasis system, activity of opioid peptides, hormonal status, vegetative and emotional parameters were studied in patients with lumbar pains of a vertebrogenic nature. The results obtained revealed a whole series of generalized shifts determining the reaction of the body to a local pain syndrome. These shifts were shown to exert an unfavourable effect on the course of a local pathological process. It is suggested that the generalized neurohumoral changes should be corrected by anti- and deaggregation agents, vasodilators, and a combination of psychotropic drugs.