Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Left ventricular performance during exercise: response of ear densitogram derivative.

B G Haffty, T Sugiura, N E O'Hare

The American Journal of Cardiology

|July 1, 1983

Summary

The peak derivative (PD) of the ear densitogram effectively tracks left ventricular (LV) function during exercise. Normal individuals show a sustained PD increase, unlike coronary artery disease patients who exhibit a rapid, short-lived response.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Statewide Multi-institutional Study of Asymptomatic Pre-Treatment Testing of Radiation Therapy Patients for SARS-CoV-2 in a High-Incidence Region of the United States.

International journal of radiation oncology, biology, physics·2021

Same author

Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol.

BMJ open·2019

Same author

Association between cytosolic expression of BRCA1 and metastatic risk in breast cancer.

British journal of cancer·2015

Same author

Tailoring cancer radiotherapy through genotyping, how close are we?

The British journal of radiology·2015

Same author

Basal subtype, as approximated by triple-negative phenotype, is associated with locoregional recurrence in a case-control study of women with 0-3 positive lymph nodes after mastectomy.

Annals of surgical oncology·2014

Same author

Dosimetric feasibility and acute toxicity in a prospective trial of ultrashort-course accelerated partial breast irradiation (APBI) using a multi-lumen balloon brachytherapy device.

Annals of surgical oncology·2012

Area of Science:

Cardiology
Physiology
Biomedical Engineering

Background:

The peak derivative (PD) of the ear densitogram is a non-invasive measure.
PD has demonstrated potential in assessing left ventricular (LV) function.

Purpose of the Study:

To evaluate the utility of PD in differentiating between normal subjects and patients with coronary artery disease (CAD) during exercise.
To characterize the dynamic changes in PD in response to exercise and recovery in these groups.

Main Methods:

Echocardiography was used to measure left ventricular function.
Peak derivative (PD) of the ear densitogram was recorded.
Subjects underwent graded exercise testing with simultaneous PD and echocardiographic measurements.

Related Experiment Videos

Main Results:

Normal subjects exhibited a gradual, consistent increase in PD throughout exercise and into 2 minutes of recovery.
Patients with coronary artery disease showed a rapid PD increase only up to 1 minute of exercise, with no further significant rise.
Significant differences in PD response between normal subjects and CAD patients were observed at multiple time points during exercise and recovery.

Conclusions:

PD serves as a valuable indicator for assessing LV function during exercise stress.
The distinct PD response patterns can help differentiate normal individuals from those with coronary artery disease.
The observed PD changes in normal subjects post-exercise may relate to heart rate recovery and LV ejection dynamics.