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Related Experiment Videos

When is myocardial mapping clinically valuable?

A H Harken, M E Josephson

    American Journal of Surgery
    |June 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Chronic, reentrant cardiac arrhythmias, often malignant, are inducible via programmed electrical stimulation. Electrophysiologic testing guides treatment, with surgery and mapping considered when drug therapy fails.

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    Area of Science:

    • Cardiology
    • Electrophysiology

    Background:

    • Cardiac arrhythmias are broadly classified as automatic or reentrant.
    • Chronic, recurrent arrhythmias are typically reentrant in nature.
    • Reentrant arrhythmias are inducible using programmed electrical stimulation.

    Purpose of the Study:

    • To outline the diagnostic and therapeutic approach to malignant cardiac arrhythmias.
    • To emphasize the role of electrophysiologic testing in guiding treatment.
    • To highlight the value of surgical intervention and mapping when pharmacologic therapy fails.

    Main Methods:

    • Induction of reentrant ventricular tachyarrhythmias using programmed electrical stimulation in an electrophysiologic laboratory.
    • Guidance of pharmacologic suppression based on electrophysiologic testing results.

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  • Preoperative endocardial catheter mapping and intraoperative electrophysiologic localization for surgical candidates.

    • Main Results:

    • Electrophysiologic testing is crucial for identifying and characterizing reentrant arrhythmias.
    • Pharmacologic suppression is guided by these electrophysiologic findings.
    • Surgical intervention becomes a viable option when antiarrhythmic drug therapy is ineffective.

    Conclusions:

    • Reentrant arrhythmias necessitate electrophysiologic study for accurate diagnosis and management.
    • Preoperative mapping and intraoperative localization are essential for successful surgical treatment of refractory arrhythmias.