Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brain electrical activity mapping (BEAM) in schizophrenic patients.

J M Morihisa, F H Duffy, R J Wyatt

    Archives of General Psychiatry
    |July 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    COMBINED DELAY AND GRAPH EMBEDDING OF EPILEPTIC DISCHARGES IN EEG REVEALS COMPLEX AND RECURRENT NONLINEAR DYNAMICS.

    Proceedings. IEEE International Symposium on Biomedical Imaging·2015
    Same author

    Prediction of dyslexia in kindergarten boys.

    Annals of dyslexia·2013
    Same author

    Linguistic profiles of dyslexic and good readers.

    Annals of dyslexia·2013
    Same author

    NIDCAP improves brain function and structure in preterm infants with severe intrauterine growth restriction.

    Journal of perinatology : official journal of the California Perinatal Association·2012
    Same author

    Rufinamide for the treatment of epileptic spasms.

    Epilepsy & behavior : E&B·2011
    Same author

    Is the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) effective for preterm infants with intrauterine growth restriction?

    Journal of perinatology : official journal of the California Perinatal Association·2010

    Brain electrical activity mapping identified distinct EEG patterns in schizophrenic patients. Both medicated and drug-free groups showed altered slow and fast brainwave activity compared to controls, enabling high classification accuracy.

    Area of Science:

    • Neuroscience
    • Psychiatry
    • Biomedical Engineering

    Background:

    • Schizophrenia is a complex psychiatric disorder with debated neurophysiological underpinnings.
    • Traditional electroencephalography (EEG) and evoked potential (EP) analyses can be complex and lack intuitive visualization.

    Purpose of the Study:

    • To introduce and evaluate brain electrical activity mapping (BEAM) as a topographic approach for analyzing EEG and EP data in schizophrenia.
    • To investigate neurophysiological differences between drug-free schizophrenic patients, medicated schizophrenic patients, and normal controls.

    Main Methods:

    • Brain electrical activity mapping (BEAM) was used to visualize EEG and EP data.
    • Eleven drug-free schizophrenic patients, 14 medicated schizophrenic patients, and 11 normal controls participated.

    Related Experiment Videos

  • Multivariate discriminant analysis and jackknifing were employed for statistical analysis and classification.

    • Main Results:

    • Schizophrenic groups exhibited increased slow (delta) activity, particularly in frontal regions, and increased fast (beta) activity in postcentral regions compared to controls.
    • Significant differences were observed in late visual evoked potentials and middle auditory evoked potentials between schizophrenic patients and controls.
    • Retrospective classification achieved 95% accuracy; prospective classification (jackknifing) yielded 84.0% for medicated and 81.8% for drug-free patients versus controls.

    Conclusions:

    • Brain electrical activity mapping is a powerful tool for visualizing and differentiating neurophysiological patterns in schizophrenia.
    • Distinct EEG and EP abnormalities are present in both medicated and drug-free schizophrenic patients, suggesting underlying stable neurophysiological markers.
    • BEAM demonstrates high potential for objective diagnosis and classification of schizophrenia.