Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Infections caused by Rhodochrous.

D R Haburchak, B Jeffery, J W Higbee

The American Journal of Medicine

|August 1, 1978

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evaluating the risk to humans from mineral oils in foods: Current state of the evidence.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2019

Same author

Validation of maternal cardiac output assessed by transthoracic echocardiography against pulmonary artery catheterization in severely ill pregnant women: prospective comparative study and systematic review.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2016

Same author

Toxicological effects of pet food ingredients on canine bone marrow-derived mesenchymal stem cells and enterocyte-like cells.

Journal of applied toxicology : JAT·2015

Same author

In vitro safety assessment of food ingredients in canine renal proximal tubule cells.

Toxicology in vitro : an international journal published in association with BIBRA·2014

Same author

Impaired vascular permeability regulation caused by the VEGF₁₆₅b splice variant in pre-eclampsia.

BJOG : an international journal of obstetrics and gynaecology·2011

Same author

Sonographic measurement of cervical length and fetal fibronectin testing in threatened preterm labor.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2006

Rhodochrous organisms may cause illness in immunocompromised patients. These bacteria, identified by their unique growth and acid-fast properties, showed increased pathogenicity in steroid-treated guinea pigs.

Area of Science:

Microbiology
Immunology
Pathogen Discovery

Background:

The
rhodochrous taxon
comprises bacteria with specific morphological and biochemical characteristics, including partial acid-fastness, Gram-positivity, and catalase positivity.
These organisms form characteristic orange or red colonies on various microbiological agars within 3-4 days.
Differentiation from related genera like Nocardia is achieved through morphological analysis and the ability to degrade ethylene glycol.

Observation:

Three immunocompromised patients yielded isolates identified as
rhodochrous taxon
, suggesting a potential role in human infections.
In vivo studies involved inoculating guinea pigs with clinical isolates and a reference strain.

Related Experiment Videos

Half the animals received methylprednisolone treatment prior to inoculation to assess the impact of immune compromise.

Findings:

Steroid-treated guinea pigs developed clinical illness, diffuse peritonitis, and allowed for the recovery of inoculated organisms.
In contrast, non-steroid-treated animals showed a more localized response, with one developing an abscess and no organism recovery.
These findings indicate that immune suppression significantly enhances the pathogenicity of
rhodochrous taxon
organisms.

Implications:

The study highlights the potential pathogenicity of
rhodochrous taxon
in clinical settings, particularly in immunocompromised individuals.
This underscores the importance of considering these organisms in the differential diagnosis of infections in susceptible patient populations.
Further research into the virulence factors and host-pathogen interactions of
rhodochrous taxon
is warranted.