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[Intracranial lipomas--report of six cases]
Insights
Intracranial lipomas are rare, especially in infants. This study details six cases, highlighting CT findings and associated conditions like corpus callosum agenesis.
Area of Science:
- Neurology
- Radiology
- Pediatrics
Background:
- Intracranial lipomas are exceptionally rare tumors.
- Infantile intracranial lipomas are reported even more infrequently.
Observation:
- The study reviewed six intracranial lipoma cases: five infants and one adult.
- Neuroradiological examinations, particularly CT scans, were analyzed.
- Common locations included the corpus callosum, quadrigeminal cistern, sylvian fissure, and interpeduncular cistern.
Findings:
- Five of the six patients were infants, with varied lipoma locations.
- Four cases were associated with agenesis of the corpus callosum.
- Specific associations noted were corpus callosum lipoma with cranium bifidum and quadrigeminal cistern lipoma with obstructive hydrocephalus.
Implications:
- Understanding the neuroradiological features of intracranial lipomas is crucial for diagnosis.
- The high association with agenesis of the corpus callosum warrants further investigation.
- This case series contributes to the limited literature on infantile intracranial lipomas.
Abstract:
Intracranial lipoma is a very rare tumor, and infantile lipoma has been reported quite scarcely. The authors recently have encountered six cases of intracranial lipoma, five are infants and one is adult, on which the results of neuroradiological examinations, especially CT findings are reported. Two of six cases had lipoma of the corpus callosum associated with cranium bifidum at the midline of frontal region. Two of six cases had lipoma occurred at the quadrigeminal cistern. To one of them showing advanced enlargement in circumference of the head in the postnatal period, the V-P shunt was conducted for obstructive hydrocephalus. Another case had agenesis of the corpus callosum associated with interhemispheric cyst. One case out of six had lipoma originating from the left sylvian fissure and the remaining adult patient had lipoma located in the interpeduncular cistern. Four cases out of those six were associated with agenesis of the corpus callosum. Based on published reports, the etiology, neuroradiological features, clinical symptoms and signs, differential diagnosis and surgical indication were discussed.