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Elbow eruptions in nickel and chromate dermatitis
Contact Dermatitis
|May 1, 1983
Summary
Systemic allergic contact dermatitis can manifest as hyperkeratotic elbow lesions in patients with nickel or chromate allergies and hand eczema. These distinct elbow symptoms mirror the course of hand dermatitis, indicating a broader allergic response.
Area of Science:
- Dermatology
- Allergology
- Pathology
Background:
- Dyshidrotic hand eczema is common, often linked to allergies.
- Nickel and chromate are frequent contact allergens.
- Elbow lesions in such patients are not well-characterized.
Purpose of the Study:
- To investigate the occurrence and characteristics of elbow lesions in patients with known nickel or chromate allergy and hand eczema.
- To determine if these elbow lesions are associated with systemic allergic contact dermatitis.
Main Methods:
- Observation of 7 patients with diagnosed nickel/chromate allergy and hand eczema.
- Clinical examination for hyperkeratotic elbow lesions.
- Histopathological analysis of skin biopsies from elbow lesions.
Main Results:
- Symmetric, hyperkeratotic elbow lesions were observed in all 7 patients.
- Elbow lesions exhibited a clinical course parallel to hand dermatitis.
- Histopathology revealed features of lichen simplex chronicus and subacute-chronic dermatitis, excluding psoriasis.
Conclusions:
- Symmetric hyperkeratotic elbow lesions represent a potential clinical sign of systemic allergic contact dermatitis.
- These elbow manifestations are characteristic in patients with underlying nickel or chromate allergies and hand eczema.