[Pharmacokinetics of bilignost in the normal liver and in experimental pathology]

In the first approximation the process of distribution of the radiographic contrast agent bilignost may be formalized with the aid of a linear two-compartmental model, while generally, with the aid of a non-linear many-compartmental perfusion model of the pharmacokinetics. Pharmacokinetic analysis of experimental data has shown that the decreased content of bilignost in the liver during acute carbon tetrachloride poisoning is largely determined by the impairment of radiographic contrast agent absorption by the liver.