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Related Experiment Videos

Lean body mass in obesity.

G B Forbes, S L Welle

    International Journal of Obesity
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Most obese individuals gain both fat and lean body mass (LBM). Intentional overfeeding also increases LBM in normal individuals, differing from some animal obesity models.

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    Area of Science:

    • Human physiology
    • Obesity research

    Background:

    • Human obesity is often characterized by increased lean body mass (LBM) alongside fat mass.
    • This contrasts with some animal models of obesity, which show decreased LBM.

    Purpose of the Study:

    • To investigate the body composition changes in human obesity.
    • To compare human obesity with animal models regarding LBM.

    Main Methods:

    • Analysis of body composition in obese individuals (children and adults).
    • Review of studies on intentional overfeeding in normal individuals.
    • Comparison with existing data on experimental and hereditary animal obesity.

    Main Results:

    • Obese individuals typically exhibit increased LBM, contributing significantly to excess weight.

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  • Intentional overfeeding in normal subjects also leads to gains in both LBM and fat.
  • Human obesity differs from certain animal models where obesity is linked to reduced LBM.

    • Conclusions:

    • Human obesity involves an increase in both fat and lean body mass.
    • This physiological response in humans distinguishes it from specific animal models of obesity.