Pyogenic granuloma (lobular capillary hemangioma) within port-wine stains

We observed two patients who developed pyogenic granulomas within port-wine stains. One had a single lesion without recurrence, whereas the second had multiple lesions that developed during a 6-year period. It has been postulated that arteriovenous anastomoses are associated with the pathogenesis of pyogenic granuloma. Formation of pyogenic granuloma within a port-wine stain, a lesion often associated with arteriovenous anastomoses, provides further support for this idea.