Nutritional considerations in the management of patients with amyotrophic lateral sclerosis (ALS)

This study examines the nutritional status of patients with ALS based on data derived from a dietary history, anthropometric measurements, and biochemical assessment. Twenty patients, 11 men and 9 women, were studied to determine nutritional status in order to differentiate appropriate therapy and monitor prognosis. The study suggests that nutritional support of these patients may help allay weight loss and retard muscle atrophy. Nutritional management involves (a) early detection and correction of inadequate nutrient intake, particularly of kilocalories; (b) concurrent modification in consistency of food intake with development of bulbar involvement; and (c) determination of optimal time to institute alternate feeding routes in cases of bulbar involvement.