[Non-Hodgkins's lymphomas - current aspects of clinical diagnosis and therapy]

Non-Hodgkin-Lymphomas (NHL), classified according to "Kiel" or Rappaport", may be subdivided into those with low or with high malignancy. Corresponding to clinical stage and to histological subtype, therapeutic recommendations are discussed. 1. Limited stage: An irradiation with curative intention seems possible. In cases with unfavourable histology relapses are frequent, and an additional or exclusive therapy with cytostatics appears to be of increasing importance. 2. Advanced stages and favourable histology: The value of an early and intensive use of cytostatics is questioned. 3. Advanced stages and unfavourable histology: Cure of the lymphoma seems feasible when intensive cytostatic regimes are applied.