Related Experiment Video
Updated: Aug 11, 2026

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents
Published on: August 10, 2014
Abstract:
ADH at doses 20 microU/100 g and 100 microU/100 g or 20 microU/100 g and 200 microU/100 g was injected intravenously into pentobarbital and alcohol anaesthetized rats loaded with either water or isotonic solution consisting of NaCl, glucose and ethanol. At the dose of 20 microU/100 g ADH retained water in both water and NaCl loaded animals. At high doses 100 microU/100 g in NaCl loaded rats and 200 microU/100 g in water loaded rats, ADH retained water and increased the renal excretion of Na+. That the natriuretic effect of ADH at the dose 20 microU/100 g was enhanced in NaCl loaded rats suggests that ADH is probably important in the regulation of Na+ content in the body when it is loaded with NaCl.
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