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Monoclonal IgA J539 binds galactopyranosyl antigens on its surface

G Ekborg, Y Ittah, C P Glaudemans

Molecular Immunology

|March 1, 1983

Abstract:

Murine monoclonal IgA J539 binds to methyl beta-D-galactopyranoside. With nearly the same affinity, it binds to methyl 6-O-pivaloyl-beta-D-galactopyranoside (4) and to methyl 6-O-beta-D-gentiobiosyl-beta-D-galactopyranoside (7). These observations confirm that the combining area of J539 is of the surface-, and not of the cavity-type.

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