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[Pseudotumor cerebri].

M Ishikawa, H Handa

    No Shinkei Geka. Neurological Surgery
    |April 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Pseudotumor cerebri, or idiopathic intracranial hypertension, can cause vision loss and requires differentiation from brain tumors. Its pathophysiology involves factors like cerebrospinal fluid absorption and blood volume, warranting further research.

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    Area of Science:

    • Neurosurgery
    • Neurology
    • Ophthalmology

    Background:

    • Pseudotumor cerebri (idiopathic intracranial hypertension) is clinically significant for differentiating from brain tumors.
    • Literature review and case series of eighteen patients are presented.
    • Lower incidence in Japan may relate to racial or dietary factors.

    Purpose of the Study:

    • To review clinical features and pathophysiology of pseudotumor cerebri.
    • To highlight diagnostic imaging utility and intracranial pressure monitoring findings.
    • To discuss potential contributing factors and areas for future research.

    Main Methods:

    • Review of clinical literature and eighteen patient cases.
    • Analysis of diagnostic imaging (CT scan, angiography) and continuous intracranial pressure monitoring.

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  • Assessment of visual acuity and other symptoms related to increased intracranial pressure.

    • Main Results:

    • Visual impairment can be severe, contrary to the "benign" perception.
    • CT scans are useful for evaluating ventricular size and densities; contrast enhancement aids lesion detection.
    • Angiography can reveal dural sinus occlusion or arteriovenous malformations; intracranial pressure monitoring shows variability.

    Conclusions:

    • Pseudotumor cerebri diagnosis requires careful differentiation from other intracranial lesions.
    • Pathophysiology may involve increased blood volume, brain edema, and impaired cerebrospinal fluid absorption.
    • Further research into cerebrospinal fluid dynamics and brain water content is needed to elucidate mechanisms.