Wernicke's encephalopathy. A case report with neurophysiologic and CT-scan studies

Area of Science:

• Neurology
• Nutritional Neuroscience

Background:

• Wernicke's encephalopathy is a serious neurological condition
• It is caused by thiamine (vitamin B1) deficiency

Observation:

• A patient presented with ataxia, confusion, memory loss, complex partial seizures, and hypothermia
• Symptoms followed chronic malnutrition, acute vomiting, and diarrhea
• CT scans revealed bilateral lesions near the third ventricle

Findings:

• The lesions observed on CT scans are consistent with typical autopsy findings in Wernicke's encephalopathy
• Early diagnosis and prompt treatment were crucial

Implications:

• Aggressive treatment with vitamin B complex and cognitive therapy can lead to full recovery
• Highlights the importance of recognizing and treating thiamine deficiency promptly
• This case underscores the link between malnutrition and severe neurological deficits