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Anticoagulation in renal vein thrombosis
Archives of Internal Medicine
|September 1, 1978
Summary
Long-term anticoagulation therapy effectively resolved renal vein thrombosis in two nephrotic syndrome patients. This treatment maintained stable kidney function, suggesting its value for similar cases.
Area of Science:
- Nephrology
- Hematology
- Vascular Medicine
Background:
- Nephrotic syndrome poses a risk for renal vein thrombosis.
- Anticoagulation is a potential treatment for venous thromboembolism.
Observation:
- Two patients with nephrotic syndrome and renal vein thrombosis were treated with long-term anticoagulation.
- Neither patient developed peripheral thromboemboli during treatment.
Findings:
- Renal vein thrombi resolved in both patients after eight months of oral anticoagulation.
- Glomerular filtration rate remained stable despite persistent nephrotic syndrome.
Implications:
- Long-term anticoagulation therapy may be beneficial for nephrotic patients experiencing renal vein thrombosis.
- This approach could help preserve renal function in this patient population.