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Idiopathic calcifying tenosynovitis. Histopathologic features and possible pathogenesis.

M B Gravanis, E F Gaffney

    The American Journal of Surgical Pathology
    |June 1, 1983
    PubMed
    Summary

    Idiopathic calcifying tenosynovitis involves cream cheese-like material within tendons. Histopathology reveals intratendinous lesions and synovial psammoma-like calcifications, likely a reactive process.

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    Area of Science:

    • Orthopedics
    • Pathology
    • Rheumatology

    Background:

    • Idiopathic calcifying tenosynovitis is a rare condition affecting tendons.
    • It presents with characteristic extratendinous calcifications.

    Purpose of the Study:

    • To describe the histopathologic findings in two cases of idiopathic calcifying tenosynovitis.
    • To elucidate the nature and origin of the calcifications observed.

    Main Methods:

    • Histopathologic examination of surgical specimens from two patients.
    • Detailed analysis of intratendinous lesions and surrounding synovial tissues.

    Main Results:

    • Cream cheese-like material was found within the affected tendons.
    • Intratendinous lesions showed varying stages of evolution, from proteinaceous material to cystic changes.

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  • No intratendinous calcification was identified.
  • Synovial and peritendinous tissues exhibited numerous psammoma-like calcifications.
  • Conclusions:

    • The synovial and peritendinous calcifications are likely a reactive response to primary tendinous pathology.
    • Potential causes for the primary tendinous lesion include ischemia or chronic mild trauma.