[Prospective study of laryngeal epitheliomas (1975-1981). Results of a multicenter study]

Cases of endolaryngeal epithelioma diagnosed during 1975 were followed up for 5 years in 23 French Laryngology Units. Precise clinical descriptions were reported in 734 cancers: of the vocal cords in 37.5 p. cent of cases and of the vestibule in 32.5 p. cent. Other localizations were observed more rarely. The T1 T2 cancers represented 83 p. cent of glottic tumors and 53 p. cent of supraglottic cancers, their proportion varying from one centre to another. Recovery chances are excellent for cancer limited to the glottic region, both radiotherapy or surgery (5-year survival: 79 p. cent). Prognosis is much poorer and almost identical for supraglottic cancers and those extending to 2 or 3 levels. An analysis of recurrences combined with a multivariate study was conducted to assess clinical and therapeutic factors influencing the course of the disease.