[The problem of the large fetus]

Morphological features of adenohypophysis and epiphysis of fetuses weighing 4.0 kg and more were studied and their morphometry was done in comparison with a control group (3.0-3.5 kg). The correlation coefficient of the fetus growth and diameter of acidophils of adenohypophysis was found to be +0.81, that of the fetus growth and acidophil nuclear-cytoplasmic ratio to be -0.70, that of the fetus growth and intensity of specific (to somatotropic hormone) immunofluorescence of adenohypophysis section to be +0.73, indicating to a strong relationship between these parameters. It is suggested that functioning of the epiphysis and intrauterine fetus growth depend on the light conditions under which the pregnant woman lives.