Related Experiment Video
Updated: Aug 9, 2026

05:59
Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury
Published on: August 30, 2019
Liver necrosis following hepatic artery transection due to trauma
Archives of Surgery (Chicago, Ill. : 1960)
|September 1, 1978
Abstract:
Hepatic artery ligation for control of bleeding liver wounds has gained widespread acceptance. Hepatic necrosis is rarely seen after this procedure has been performed. Recently, a patient with multiple organ injuries secondary to a gunshot wound to the abdomen underwent hepatic artery ligation and hepatic necrosis developed even though the portal venous system was normal.
Related Concept Videos
Liver Regeneration
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...
Cirrhosis II: Pathophysiology
Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...

