Related Experiment Video
Updated: Aug 17, 2026

A Computational Modeling Approach to Investigate the Influence of Hyperthermia on the Tumor Microenvironment
Published on: December 1, 2023
[Cooperative thermal transitions in normal and tumor cells]
Abstract:
It is established that chromatin denaturation in the cell composition under conditions approximating to equilibrium is a quasistatistical process. It is shown that thermal treatment of tissues in chromatin composition enables to reveal the thermostable block with the following parameters of denaturation Td = 89 degrees C, Td = 3.5 degrees C and Qd = (28 +/- 4) J/g DNA. It is discovered that thermostability of tumor chromatin increases compared with the normal one, and this value in case of leucosis fluctuates from 5 degrees C to 10 degrees C, but in the case of sarcomas and ascite hepatoma of rats and mice it fluctuates from 2 degrees to 5 degrees C.
More Related Videos
09:04Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
06:42Plasmonic Photothermal Cancer Therapy: Nanoparticle-embedded Tumor-tissue-mimicking Phantoms for Visualizing Photothermal Temperature Distribution
Published on: May 9, 2025
Related Concept Videos
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
The Tumor Microenvironment
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
The Tumor Microenvironment