[Effect of clofibrate on the enzyme activity of the rat small intestine epithelium]

The effect of chronic administration of clofibrate on the enzyme activity of male rat small intestine homogenate was studied. The activities of peroxisomal and mitochondrial fatty acyl-CoA beta-oxidation enzymes were induced by clofibrate treatment. The activities of catalase, carnitine acetyltransferase and some other enzymes were also increased. Clofibrate did not affect the polypeptide composition of the "post-nuclear" small intestine homogenate.