Reduced protein loss during hemofiltration using Cuprophan membranes

In a study of four patients treated with one hour of hemofiltration using Cuprophan membranes, followed by three hours of hemodialysis, it was found that protein loss during hemofiltration was minimal. Losses ranged from 0.013 mg/mg at a transmembrane pressure (TMP) of 300 mmHg to 0.012 mg/ml at a TMP of 600 mmHg. Protein loss was not dependent on TMP and varied from dialyzer to dialyzer. Protein levels in serum remained unchanged during the period of hemofiltration in these patients and no evidence of protein wastage was evident.