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Related Experiment Videos

[Immunoglobulins in bilharziasis].

A Abouzkham, G Lebeau, J C Petithory

    Bulletin De La Societe De Pathologie Exotique Et De Ses Filiales
    |March 1, 1983
    PubMed
    Summary

    Elevated immunoglobulin E (IgE) suggests Schistosomiasis in 68% of cases. Immunoglobulin G (IgG) increases across all Schistosoma types, while IgM rises in hepatosplenic disease from Schistosoma mansoni.

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    [Familial eosinophilia: contribution of parasitology to its diagnosis].

    Bulletin de l'Academie nationale de medecine·1999

    Area of Science:

    • Immunology
    • Infectious Diseases
    • Parasitology

    Context:

    • Schistosomiasis is a significant parasitic disease affecting millions globally.
    • Accurate diagnostic markers are crucial for timely treatment and disease management.
    • Immunoglobulin levels are key indicators in parasitic infections.

    Purpose:

    • To investigate the diagnostic utility of immunoglobulin levels in identifying Schistosomiasis.
    • To correlate specific immunoglobulin changes (IgE, IgG, IgM, IgA) with different Schistosoma species and disease manifestations.

    Summary:

    • Increased immunoglobulin E (IgE) levels are indicative of Schistosomiasis in 68% of cases.
    • Immunoglobulin G (IgG) elevation is observed in all forms of Schistosomiasis, including Schistosoma mansoni, Schistosoma haematobium, and Schistosoma intercalatum.
    • Elevated immunoglobulin M (IgM) is specifically associated with hepatosplenic disease caused by Schistosoma mansoni.
    • No significant alterations in immunoglobulin A (IgA) levels were detected.

    Impact:

    • Provides valuable insights into the role of specific immunoglobulins as biomarkers for Schistosomiasis diagnosis.
    • Highlights the potential of IgE and IgG as general indicators and IgM as a specific marker for certain Schistosomiasis-related conditions.
    • Contributes to improved diagnostic strategies for Schistosomiasis, particularly in endemic regions.

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