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Tri-axial ellipsoids as models for macromolecules in solution: procedures for numerical inversion of the shape
Computers in Biology and Medicine
|January 1, 1983
Abstract:
Two FORTRAN IV algorithms are given for determining the two axial ratios of a macromolecule (as modelled by a tri-axial ellipsoid) from its hydrodynamic parameters. The first involves a simple graphical inversion procedure of the volume independent V and R functions but can only be applied to a restricted range of macromolecules. The second algorithm is more general and involves an R-function constrained non-linear least squares fit to birefringence decay data.