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Published on: June 11, 2019
Severe anaemia: its CT findings in the cardiovascular system
Insights
Computed tomography (CT) effectively visualized heart and great vessel morphology in severe anemia patients without contrast. CT scans showed no cardiac hemochromatosis but suggested liver hemochromatosis in several cases.
Area of Science:
- Radiology
- Cardiology
- Gastroenterology
Background:
- Severe anemia can affect cardiac and hepatic structures.
- Computed tomography (CT) is a valuable imaging modality for assessing organ morphology.
Purpose of the Study:
- To evaluate the utility of non-contrast CT in visualizing cardiac and upper abdominal structures in patients with severe anemia.
- To assess for signs of hemochromatosis in the heart and liver using CT.
Main Methods:
- Computed tomography (CT) of the upper abdomen and heart was performed on 21 patients with severe anemia.
- Gross morphology, including wall thickness, chamber size, and vessel dimensions, was assessed.
- CT density measurements were used to evaluate for hemochromatosis.
Main Results:
- Cardiac and great vessel morphology were visualized in all patients without contrast media.
- No CT signs of cardiac hemochromatosis were observed.
- CT measurements were highly suggestive of liver hemochromatosis in several patients.
Conclusions:
- Non-contrast CT is effective for visualizing cardiac and upper abdominal structures in severe anemia.
- CT can help identify liver hemochromatosis, but visual assessment of liver density can be misleading.
- Further investigation is warranted for suspected liver hemochromatosis identified by CT.
Abstract:
Computed tomography of the upper abdomen and of the heart was performed in 21 patients with severe anemia (mean haematocrit value 0.23, mean haemoglobin content 39.6%). Gross morphology of the heart and great vessels (wall thickness, size of the chambers, lumina and walls of the vessels) were visualized in all patients without the use of contrast media. The smallest discernible difference between the normal heart muscle and blood filling its cavities was about 6-8 H and the smallest discernible difference between the aorta and the aortic blood was about 8-10 H (window width 150 H, window level 50 H). There were no CT signs of haemochromatosis of the heart, while CT measurements were highly suggestive of liver haemochromatosis in several cases. Visual evaluation of liver density in comparison to the density of blood in hepatic and portal vessels is misleading.
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