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Synthesis of 3-dialkylaminopropyl-2-thiohydant derivatives as potential antiarrhythmic agents
Abstract:
A series of 3-dialkylaminopropyl-5-monosubstituted-2-thiohydantoins were synthesized as potential antiarrhythmic agents; their pharmacological activity is comparable to that of quinidine, but weaker than that of phenytoin.
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