Related Experiment Video
Updated: Sep 27, 2026

10:22
Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
Published on: September 16, 2011
Presence of basophils in PHA-reacted skin sites of mice. An electron microscopic study
Abstract:
Subcutaneous injections of the lymphocyte mitogen PHA in mice induced a local reaction which was delayed in time course and characterized histologically by dermal infiltration with blood granulocytes. Basophils were identified in the skin sections by electron microscopy as their granules differ from those of other blood granulocytes and tissue mast cells.

