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[Acute respiratory insufficiency in polyneuritis].

M D Rangel Carrillo, J F Tello Guzmán, O Muñóz Hernánsez

    Boletin Medico Del Hospital Infantil De Mexico
    |November 1, 1978
    PubMed
    Summary

    Severe respiratory distress in polyneuritis is lethal, but positive pressure ventilation and tracheostomy reduced mortality from 40% to 0%. Positive End-Expiratory Pressure (PEEP) was key to correcting hypoxemia.

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    Area of Science:

    • Medical Science
    • Pulmonology
    • Neurology

    Context:

    • Polineuritis can lead to severe respiratory distress, a primary cause of mortality.
    • A retrospective study was conducted at Hospital de Pediatría del Centro Médico Nacional.
    • The study involved 13 cases of polineuritis with respiratory complications.

    Purpose:

    • To evaluate the effectiveness of positive pressure ventilation and tracheostomy in reducing lethality associated with respiratory distress in polineuritis.
    • To explore the role of positive end-expiratory pressure (PEEP) in managing hypoxemia in these patients.

    Summary:

    • Lethality in polineuritis is directly linked to severe respiratory distress.
    • The implementation of positive pressure ventilation and tracheostomy reduced mortality from 40% to 0% in severe cases.
    • Positive end-expiratory pressure (PEEP) was utilized to correct hypoxemia by addressing ventilation/perfusion (V/Q) mismatches.

    Impact:

    • Demonstrates a significant reduction in mortality for polineuritis patients with respiratory distress through specific interventions.
    • Highlights the therapeutic potential of PEEP in improving oxygenation in critical respiratory conditions.
    • Provides evidence for improved clinical outcomes in severe polineuritis cases.

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