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Related Experiment Videos

Flexor tenosynovitis caused by Coccidioides immitis.

P T Gropper, W A Pisesky, V Bowen

    The Journal of Hand Surgery
    |May 1, 1983
    PubMed
    Summary

    Coccidioidomycosis is a rare fungal infection. This case report details coccidioidal tenosynovitis in an immunocompromised patient, recommending amphotericin B and surgery for treatment.

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    Area of Science:

    • Mycology
    • Infectious Diseases
    • Rheumatology

    Background:

    • Coccidioidomycosis is a systemic fungal infection endemic to arid regions of the Americas.
    • Disseminated coccidioidomycosis is rare, occurring in less than 0.1% of pulmonary infections.
    • Immunosuppressive chemotherapy increases the risk of disseminated fungal infections.

    Observation:

    • A case of coccidioidal tenosynovitis is presented.
    • The patient was undergoing immunosuppressive chemotherapy.
    • This represents a rare manifestation of disseminated coccidioidomycosis.

    Findings:

    • Coccidioidal tenosynovitis occurred in an immunosuppressed patient.
    • Dissemination of pulmonary coccidioidomycosis to the tenosynovium is an uncommon event.
    • The infection was successfully treated with a combination of antifungal therapy and surgical intervention.

    Implications:

    • Highlights the importance of considering disseminated fungal infections in immunocompromised patients.
    • Emphasizes the need for prompt diagnosis and aggressive management of rare coccidioidal manifestations.
    • Suggests that combined intravenous amphotericin B and surgical synovectomy is an effective treatment strategy.

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