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Related Experiment Videos

Lactose enhances mineral absorption in infancy.

E E Ziegler, S J Fomon

    Journal of Pediatric Gastroenterology and Nutrition
    |May 1, 1983
    PubMed
    Summary

    Lactose significantly enhances mineral absorption in infants. Studies show lactose in infant formula boosts calcium, magnesium, and manganese absorption, aiding overall nutrient retention.

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    Area of Science:

    • Pediatric Nutrition
    • Gastrointestinal Physiology

    Background:

    • Infant nutrition relies on optimal mineral absorption for growth and development.
    • The role of specific carbohydrates, like lactose, in nutrient bioavailability is crucial for infant health.

    Purpose of the Study:

    • To investigate the effect of lactose on the intestinal absorption of essential minerals in infants.
    • To compare mineral absorption rates between infant formulas with and without lactose.

    Main Methods:

    • Metabolic balance studies were conducted on six healthy infants.
    • Infants received two nearly identical formulas in alternating sequences: one with lactose, the other with sucrose and corn starch hydrolysate.

    Main Results:

    • Lactose significantly increased net absorption and retention of calcium.
    • Lactose also significantly enhanced the absorption of magnesium and manganese.
    • While not statistically significant, copper and zinc absorption were slightly higher with lactose; iron absorption was unaffected. Phosphorus absorption was similar, but retention improved due to reduced urinary excretion.

    Conclusions:

    • Lactose consumption in infant formulas promotes significant and sustained absorption of calcium and other minerals.
    • These findings support the beneficial role of lactose in infant mineral bioavailability, consistent with animal and previous human studies.

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