[Pulmonary metastasis of renal cell carcinoma]

I treated 116 patients with pulmonary metastasis from renal cell carcinoma (312 cases). My experience with anticancer chemotherapy indicates that complete response was elicited in 1/15, 0/14, 0/10, 1/6, 0/5 and 0/20 of cases receiving Ft-207, CCNU, vinblastine, adriamycin, ifosfamide and MFC, respectively. Progesterone therapy produced complete response in one of 60 and partial response in 2 of 60. Interferon therapy was effective in 2 of 10 cases. Surgical removal of pulmonary metastatic lesion was done in only 6% (7/116) of cases, which was worth trying especially in low grade cases. The 3 and 5 year survival Jap. rates for the entire 116 cases were 20% and 6%, respectively.