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Related Experiment Videos

[Primary multiple malignant tumors associated with bladder cancer].

I Fukui, M Yokokawa, F Ohwada

    Gan No Rinsho. Japan Journal of Cancer Clinics
    |June 1, 1983
    PubMed
    Summary

    A significant number of urothelial bladder cancer patients also have other primary cancers, with a notable increase in recent years. This highlights the importance of considering secondary malignancies in bladder cancer patients.

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    α-D-Glucosyl Transfer to Phenolic Compounds by Sucrose Phosphorylase from Leuconostoc mesenteroides and Production of α-Arbutin.

    Bioscience, biotechnology, and biochemistry·2016

    Area of Science:

    • Uro-oncology
    • Cancer epidemiology

    Context:

    • Investigating the prevalence and characteristics of secondary primary malignancies in patients diagnosed with urothelial bladder cancer.
    • Analyzing trends in double cancer diagnoses over a 22-year period.

    Purpose:

    • To determine the incidence of other primary malignant tumors in patients with urothelial bladder cancer.
    • To characterize the types, timing, and demographics of these secondary cancers.

    Summary:

    • Out of 487 urothelial bladder cancer patients, 37 (7.6%) had other primary malignant tumors.
    • The incidence of double cancer has increased recently. The mean age for the second cancer diagnosis was 70 years.
    • Digestive (47%) and respiratory (18%) tracts were the most common sites for secondary cancers. Diagnoses were synchronous in 6 and metachronous in 31 patients, with a mean interval of 9 years and 7 months.

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    Impact:

    • Findings underscore the clinical significance of co-occurring malignancies in bladder cancer patients.
    • Highlights the need for vigilant screening and management of secondary cancers in this population.
    • Provides epidemiological data on double cancer in urothelial carcinoma, informing future research and clinical practice.