Related Experiment Videos
Nephropathy induced in rats by repeated intravenous injections of rabbit anti-FX1A antibody
The Japanese Journal of Experimental Medicine
|February 1, 1983
Abstract:
Repeated intravenous injections of small amounts of rabbit anti-rat FXIA antibodies (RAFA) induced a renal damage with the morphological features of epimembranous glomerulonephritis with significant and persistent proteinuria. These findings indicated that repeatedly injected RAFA accumulated in glomeruli and that there seems to be a threshold in quantity of RAFA localized in glomeruli to induce renal damage with proteinuria.