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Auditory brainstem responses in neurologically abnormal infants.

C L Fawer, L M Dubowitz, M I Levene

    Neuropediatrics
    |May 1, 1983
    PubMed
    Summary
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    Abnormal auditory brainstem responses (ABR) are common in neurologically impaired newborns, particularly those with intraventricular hemorrhage. ABR may help assess neurological function and hearing deficits in infants.

    Area of Science:

    • Neonatal Neurology
    • Neurodevelopmental Pediatrics
    • Auditory Neuroscience

    Background:

    • Neurological abnormalities in newborns can impact development.
    • Auditory brainstem responses (ABR) are used to assess auditory pathway function.
    • Early identification of neurological deficits is crucial for intervention.

    Purpose of the Study:

    • To investigate the incidence and patterns of abnormal auditory brainstem responses (ABR) in neurologically abnormal infants.
    • To determine the correlation between ABR abnormalities and specific neurological conditions in neonates.
    • To evaluate the potential of ABR as an early diagnostic tool for neurological and hearing impairments.

    Main Methods:

    • Retrospective analysis of auditory brainstem responses (ABR) in 59 infants with neurological abnormalities.

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  • Comparison of ABR results between neurologically abnormal and optimal newborn infants.
  • Correlation of ABR findings with specific neurological conditions, including intraventricular hemorrhage, apnoeic syndrome, abnormal tone, and birth asphyxia.
  • Main Results:

    • Abnormal ABRs were observed in 33 of 59 neurologically abnormal infants (56%), compared to 5% in controls.
    • ABR abnormalities were most frequent in infants with intraventricular hemorrhage (17/21).
    • Abnormal ABRs were also frequent in infants with apnoeic syndrome (5/8) and abnormal tone (7/13); no correlation with hemorrhage size was found.
    • Infants with birth asphyxia had normal ABRs.
    • No correlation was found between the degree of ABR abnormality and the severity of clinical signs in infants with midbrain signs.

    Conclusions:

    • Abnormal auditory brainstem responses (ABR) are prevalent in neurologically impaired newborns, especially those with intraventricular hemorrhage.
    • ABR serves as a valuable tool for assessing neurological function and identifying hearing deficits in infants.
    • Further research is needed to elucidate the relationship between ABR abnormalities and primary neurological defects versus secondary lesions, and to establish prognostic implications.