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Related Experiment Videos

Computed tomography for diagnosis of persistent hyperplastic primary vitreous (PHPV).

M F Goldberg, M Mafee

    Ophthalmology
    |May 1, 1983
    PubMed
    Summary

    Computed tomography (CT) effectively diagnoses persistent hyperplastic primary vitreous (PHPV) in leucocoric eyes. Key findings include retrolental tissue enhancement and characteristic vitreous abnormalities on CT scans.

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    Area of Science:

    • Ophthalmology
    • Radiology
    • Medical Imaging

    Background:

    • Persistent hyperplastic primary vitreous (PHPV) is a congenital eye disorder.
    • Accurate diagnosis is crucial for appropriate management and visual prognosis.

    Observation:

    • Computed tomography (CT) was utilized to examine leucocoric eyes with PHPV.
    • Intravenous contrast agents and specific patient positioning (lateral decubitus) were employed to maximize diagnostic yield.

    Findings:

    • CT identified radiodense retrolental tissue enhancing with contrast, congenital retinal nonattachment, and vitreous abnormalities.
    • Layered retrohyaloid fluid, shifting with position, was noted as a potentially unique finding.
    • Absence of calcification and demonstration of ocular malformations like microphthalmos were also observed.

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    Implications:

    • CT provides valuable insights into the radiological features of PHPV.
    • These findings aid in differentiating PHPV from other pediatric ocular conditions.
    • Further studies are needed to confirm pathognomonic signs for PHPV on CT.