[Functional interaction between the determinant and other foci of epileptiform activity created in the cortex of both...

It was shown in experiments on cats under nembutal anesthesia that creation of a hyperactive focus with a high excitation level in the orbital or coronary cortex of one hemisphere and of a number of foci in the neocortex of the contralateral hemisphere led to formation of a functional complex working in a unified regimen determined by the hyperactive focus activity. The latter plays the role of a determinant structure. Suppression of the determinant focus with nembutal was followed by a decay of the epileptic complex. Section of the corpus callossum (its rostral part) led to derangement in synch ronization of the work between the determinant and other epileptic activity foci. The results of investigation confirmed the conception on the role of the determinant structure in the nervous system activity.