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Heparin-associated priapism.

B J Burke, G L Scott, P J Smith

    Postgraduate Medical Journal
    |May 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Priapism, a prolonged erection, can occur after heparin treatment. Abnormal platelet aggregation during heparin therapy may cause this rare side effect.

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    Area of Science:

    • Cardiovascular Medicine
    • Hematology
    • Urology

    Background:

    • Heparin is a widely used anticoagulant medication.
    • Priapism is a medical emergency characterized by prolonged penile erection.
    • Heparin-induced thrombocytopenia (HIT) is a known complication of heparin therapy.

    Observation:

    • A patient developed priapism 7 hours after discontinuing an intravenous heparin infusion.
    • The patient exhibited abnormal spontaneous platelet aggregation during heparin treatment.

    Findings:

    • The observed priapism is potentially linked to heparin administration.
    • Abnormal platelet aggregation during heparin therapy is hypothesized as a contributing factor to heparin-induced priapism.

    Implications:

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    • This case highlights a potential, albeit rare, adverse effect of heparin.
    • Further research may elucidate the mechanisms of heparin-induced priapism.
    • Clinicians should be aware of priapism as a possible complication in patients receiving heparin.