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Haloperidol-induced plasticity of axon terminals in rat substantia nigra
Science (New York, N.Y.)
|September 2, 1983
Abstract:
An electron micrographic morphometric analysis of nerve endings in substantia nigra of rats repeatedly treated with haloperidol was performed. Although most parameters showed no difference, drug-treated animals exhibited a significant shift in the distribution of relative numbers of axon terminals, suggesting neuroleptic-induced axon-collateral sprouting.