Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Progressive multifocal leuco-encephalopathy.

R Sandyk

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |August 27, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Progressive multifocal leukoencephalopathy (PML) is a fatal central nervous system viral infection causing widespread brain lesions. Currently, no effective therapy exists for this rapidly evolving neurological disorder.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Resolution of partial cataplexy in multiple sclerosis by treatment with weak electromagnetic fields.

    The International journal of neuroscience·1996
    Same author

    Chronic relapsing multiple sclerosis: a case of rapid recovery by application of weak electromagnetic fields.

    The International journal of neuroscience·1995
    Same author

    Reversal of visuospatial deficit on the Clock Drawing Test in Parkinson's disease by treatment with weak electromagnetic fields.

    The International journal of neuroscience·1995
    Same author

    Improvement of body image perception in Parkinson's disease by treatment with weak electromagnetic fields.

    The International journal of neuroscience·1995
    Same author

    Weak electromagnetic fields improve body image perception in patients with multiple sclerosis.

    The International journal of neuroscience·1995
    Same author

    Weak electromagnetic fields restore dream recall in patients with multiple sclerosis.

    The International journal of neuroscience·1995

    Area of Science:

    • Neurology
    • Virology
    • Immunology

    Background:

    • Progressive multifocal leukoencephalopathy (PML) is a rare, fatal demyelinating disease of the central nervous system.
    • PML typically affects adults with compromised immune systems, often due to chronic neoplastic or granulomatous diseases.
    • The condition is characterized by rapid neurological decline and widespread lesions in the cerebral hemisphere.

    Purpose of the Study:

    • To provide a comprehensive overview of Progressive Multifocal Leukoencephalopathy (PML).
    • To discuss the etiology, clinical presentation, diagnostic indicators, and current therapeutic limitations of PML.

    Main Methods:

    • Review of existing literature on PML.
    • Analysis of clinical and pathological findings associated with PML.

    Related Experiment Videos

  • Discussion of diagnostic tools, particularly electroencephalography (EEG).

    • Main Results:

    • PML is a severe demyelinating viral infection caused by papovaviruses, including JC virus and SV40-like agents.
    • Electroencephalography (EEG) is identified as the most valuable laboratory investigation for assessing pathological involvement severity.
    • The disease typically presents rapidly in immunocompromised individuals, often with a poor prognosis.

    Conclusions:

    • PML is a significant neurological challenge with no effective treatment options currently available.
    • Understanding the viral agents and disease progression is crucial for potential future therapeutic strategies.
    • Further research is needed to develop effective therapies for this devastating condition.