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[Plasmapheresis in 2 children with Guillain-Barré syndrome]
Insights
Plasmapheresis effectively treated two children with rapidly progressing Guillain Barré Syndrome (GBS), leading to significant clinical recovery. This suggests plasmapheresis is a viable treatment option for severe pediatric GBS cases.
Area of Science:
- Neurology
- Pediatric Neurology
- Immunology
Background:
- Guillain Barré Syndrome (GBS) is an acute, progressive idiopathic polyradiculoneuropathy affecting the peripheral nervous system.
- Rapidly progressive GBS in children presents significant clinical challenges and necessitates effective therapeutic interventions.
Observation:
- This study describes the clinical course of two young patients diagnosed with acute progressive idiopathic polyradiculoneuropathy.
- The patients exhibited a rapidly progressive disease course, prompting the consideration of advanced treatment modalities.
Findings:
- Plasmapheresis was administered to the two pediatric patients due to the progressive nature of their GBS.
- Following plasmapheresis treatment, both patients demonstrated a remarkable and significant clinical recovery.
Implications:
- The positive outcomes observed in these pediatric cases suggest that plasmapheresis is a beneficial treatment for Guillain Barré Syndrome.
- These findings support the serious consideration of plasmapheresis as a therapeutic option for children experiencing rapidly progressive GBS.
- Further research and case reports are warranted to solidify the role of plasmapheresis in pediatric GBS management.
Abstract:
The clinical course in two young patients, suffering from acute progressive idiopathic polyradiculoneuropathy, the Guillain Barré Syndrome, is described. In view of the progressive course, plasmapheresis was applied. After plasmapheresis we noted a remarkable clinical recovery. Those observations are compatible with several case reports in the literature. In our view plasmapheresis deserves also in children serious consideration in the treatment of rapidly progressive cases of GBS.