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Hepatitis B surface antigen in blood donors. An epidemiologic study
Transfusion
|July 1, 1983
Summary
Hepatitis B virus (HBV) screening of 8085 blood donors found 1.27% positive for hepatitis B surface antigen (HBsAg). Higher rates were observed in men, younger adults, and those from lower socioeconomic backgrounds.
Area of Science:
- Virology
- Public Health
- Epidemiology
Background:
- Hepatitis B virus (HBV) infection is a significant global health concern.
- Hepatitis B surface antigen (HBsAg) is a key serological marker for HBV infection.
- Blood donor screening is crucial for preventing transfusion-transmitted HBV.
Purpose of the Study:
- To determine the prevalence of hepatitis B surface antigen (HBsAg) carrier state among volunteer blood donors.
- To identify demographic and socioeconomic factors associated with HBsAg positivity.
Main Methods:
- Screening of 8085 volunteer blood donors using counterimmunoelectrophoresis for HBsAg.
- Analysis of personal data including sex, age, and socioeconomic status.
Main Results:
- A total of 103 (1.27%) donors were HBsAg positive.
- HBsAg positivity was higher in men compared to women.
- The 21-30 years age group showed a higher prevalence.
- Donors from lower socioeconomic groups had a significantly higher rate of HBsAg positivity (p < 0.05).
Conclusions:
- The prevalence of HBsAg among blood donors at SCTIMST was 1.27%.
- Men, younger adults (21-30 years), and individuals from lower socioeconomic strata represent key demographics for targeted screening and intervention efforts.
- These findings underscore the importance of continued vigilance in blood donor screening to ensure transfusion safety.